Klaus-Peter Zimmer Selected Research

Sucrase (Sucrose alpha-D-Glucohydrolase)

9/2019	Heterozygotes Are a Potential New Entity among Homozygotes and Compound Heterozygotes in Congenital Sucrase-Isomaltase Deficiency.
3/2009	Compound heterozygous mutations affect protein folding and function in patients with congenital sucrase-isomaltase deficiency.
12/2003	Congenital sucrase-isomaltase deficiency because of an accumulation of the mutant enzyme in the endoplasmic reticulum.

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Klaus-Peter Zimmer Research Topics

Disease

12	Celiac Disease (Celiac Sprue) 02/2022 - 12/2004
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 04/2018
4	congenital Sucrase-isomaltase deficiency 09/2019 - 12/2003
4	Inflammation (Inflammations) 01/2019 - 12/2008
3	Birth Weight (Birth Weights) 02/2022 - 01/2021
3	Bronchopulmonary Dysplasia 10/2021 - 01/2019
3	Wounds and Injuries (Trauma) 10/2021 - 01/2002
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 08/2004
3	Infections 05/2019 - 01/2015
3	Asthma (Bronchial Asthma) 05/2019 - 07/2008
3	Gaucher Disease (Gaucher's Disease) 05/2006 - 11/2005
2	Hyperoxia 10/2021 - 01/2017
2	Constipation 01/2021 - 01/2021
2	Short Bowel Syndrome 01/2020 - 01/2018
2	Hypertension (High Blood Pressure) 05/2019 - 05/2015
2	Diarrhea 01/2019 - 12/2015
2	Neoplasms (Cancer) 10/2011 - 02/2002
2	Ileitis 12/2008 - 10/2007
1	Hepatomegaly 04/2022
1	Fibrosis (Cirrhosis) 04/2022
1	Body Weight (Weight, Body) 01/2022
1	Pneumonia (Pneumonitis) 10/2021
1	Lung Injury 10/2021
1	Hypoxia (Hypoxemia) 10/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2021
1	Overweight 02/2021
1	Weight Gain 02/2021
1	HELLP Syndrome 01/2021
1	Abdominal Pain (Pain, Abdominal) 01/2021
1	Hemolysis 01/2021
1	Pre-Eclampsia (Preeclampsia) 01/2021
1	Crohn Disease (Crohn's Disease) 01/2021
1	Iron Deficiencies 11/2019
1	Diabetes Mellitus 05/2019
1	Heart Failure 05/2019
1	Human Influenza (Influenza) 05/2019
1	Rickets (Rachitis) 05/2019
1	Chronic Disease (Chronic Diseases) 05/2019
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 05/2019
1	Multiple Sclerosis 05/2019
1	Mediastinal Emphysema (Pneumomediastinum) 04/2018
1	Acidosis 01/2018
1	Intestinal Failure 01/2018
1	Rare Diseases (Rare Disease) 01/2018
1	Anemia 01/2017
1	Channelopathies 08/2016

Drug/Important Bio-Agent (IBA)

6	EnzymesIBA 04/2022 - 12/2003
5	AntigensIBA 05/2016 - 08/2004
5	Glutens (Glutelin)IBA 01/2014 - 11/2009
4	GliadinIBA 02/2022 - 12/2004
4	OvalbuminIBA 12/2008 - 03/2005
3	SteroidsIBA 02/2022 - 01/2013
3	Protein Glutamine gamma Glutamyltransferase 2IBA 02/2022 - 12/2013
3	Oxygen (Dioxygen)IBA 10/2021 - 01/2021
3	CarbohydratesIBA 01/2021 - 01/2018
3	Sucrase (Sucrose alpha-D-Glucohydrolase)IBA 09/2019 - 12/2003
3	Oligo-1,6-Glucosidase (Isomaltase)IBA 09/2019 - 12/2003
3	SodiumIBA 01/2019 - 12/2015
3	Phenobarbital (Luminal)FDA Link 05/2016 - 02/2006
3	Glucosylceramidase (Glucocerebrosidase)IBA 05/2006 - 11/2005
2	Triglycerides (Triacylglycerol)IBA 04/2022 - 02/2021
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021 - 10/2021
2	Surface-Active Agents (Surfactants)IBA 01/2021 - 01/2017
2	AutoantibodiesIBA 08/2015 - 12/2013
2	Immunoglobulin A (IgA)IBA 08/2015 - 02/2011
2	AntibodiesIBA 08/2015 - 09/2009
2	Proteins (Proteins, Gene)FDA Link 12/2004 - 01/2002
1	GlycogenIBA 04/2022
1	Ferritins (Ferritin)IBA 04/2022
1	TransglutaminasesIBA 02/2022
1	Peptides (Polypeptides)IBA 02/2022
1	SugarsIBA 02/2021
1	FructoseIBA 02/2021
1	Immunologic Factors (Immunomodulators)IBA 01/2021
1	IronIBA 11/2019
1	ZincIBA 11/2019
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 11/2019
1	Vitamin D FDA LinkGeneric 05/2019
1	CalciumIBA 05/2019
1	Fibroblast Growth Factor 10IBA 01/2019
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 01/2019
1	prostasinIBA 01/2019
1	matriptaseIBA 01/2019
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Starch (Cornstarch)IBA 01/2018
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2018
1	Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA 01/2017
1	IgA receptor (protein B)IBA 01/2017
1	Hemoglobins (Hemoglobin)IBA 01/2017
1	LigandsIBA 01/2017

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2012
3	Artificial Respiration (Mechanical Ventilation) 10/2020 - 04/2018
3	Gluten-Free Diet 01/2017 - 10/2011
2	Continuous Positive Airway Pressure 10/2020 - 01/2019
1	Enteral Nutrition (Feeding, Tube) 01/2022
1	Aftercare (After-Treatment) 01/2021
1	Bathroom Equipment 01/2021
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 10/2020
1	Parenteral Nutrition 01/2018